Synchrotron infrared beamlines use the diffraction-limited beam properties to enable a variety of cutting edge science - how can we go further? I will describe two new techniques we have recently demonstrated. First, 3D FTIR tomography  provides spectrally rich, label-free, nondestructive visualizations of distinctive chemical compositions throughout intact biological or materials samples. And Synchrotron Infrared Nano Spectroscopy (SINS)  couples the synchrotron infrared beam to the tip of an atomic force microscope (AFM) to measure very broadband (700 - 6000 cm-1) spectra from a spot only ~20 nm in size .
 Martin et al., Nature Methods, 10, 861-864 (2013).
 Bechtel et al., PNAS, under review (2014).